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UID:10001461-1771243200-1771246800@engineering.wisc.edu
SUMMARY:BME Seminar Series: Wally Block\, PhD
DESCRIPTION:*Speaker Change\n\n\n\nGene Therapy for Rare Neurodegenerative Diseases: RARE will get us there\n\n\n\n\n\n\n\nWally Block\, PhDProfessorDepartment of Biomedical EngineeringUW-Madison \n\n\n\nRare monogenic neurological diseases affect about 0.5% of Americans at birth and are estimated to account for up to 40% of the workload in hospital pediatric practice. Current drug delivery methods struggle to overcome the Blood Brain Barrier (BBB)\, with 98% of small molecule drugs and 99% of monoclonal antibody therapies failing to cross the BBB. This barrier\, while protecting the brain\, creates significant challenges for drug delivery and patient treatment. \n\n\n\nConvection Enhanced Delivery (CED) is emerging as a promising solution\, circumventing the BBB with direct\, minimally invasive catheter-based infusion. Current CED surgical protocols distribute gene therapies are transforming the outlook for Huntington’s disease where only perhaps 1% of the brain needs to be altered genetically. In most rare neurodegenerative diseases however\, much larger volumes of the brain require will require treatment. \n\n\n\nNew government initiatives like ARPA-H THRIVE are making a 9-figure investment in genetic correction\, many of which will be focused on genetic correction for rare brain disorders. This talk will provide an overview of the biophysics technology being developed across a consortium centered at UW-Madison to get from 1% to 100% of brain coverage. The talk will present an argument why solving rare diseases will accelerate efforts to treat genetic approaches to much higher prevalence diseases such as Parkinson’s or Alzheimers. \n\n\n\nPrint PDF
URL:https://engineering.wisc.edu/event/bme-seminar-series-wally-block-phd/
LOCATION:1003 (Tong Auditorium) Engineering Centers Building\, 1550 Engineering Drive\, Madison\, WI\, 53706\, United States
CATEGORIES:Biomedical Engineering,Seminar
ATTACH;FMTTYPE=image/jpeg:https://engineering.wisc.edu/wp-content/uploads/2024/11/Seminar-Graphic-Fall2024-1.avif
ORGANIZER;CN="Department of Biomedical Engineering":MAILTO:bmehelp@bme.wisc.edu
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LAST-MODIFIED:20260204T165305Z
UID:10001453-1771545600-1771804799@engineering.wisc.edu
SUMMARY:Lean Green Belt Training
DESCRIPTION:On campus – location TBD \n\n\n\nIISE is hosting in-person Lean Green Belt Training on campus!  Open to ALL students\, this is a fantastic opportunity to add an industry-recognized certification to your resume.This 3-day\, live\, in-person workshop is open to all students and focuses on practical\, engineering-driven Lean tools\, process improvement\, and data-driven problem solving—skills employers actively look for in engineering\, operations\, supply chain\, consulting\, and analytics roles. Unlike many professional certifications\, no prior industry experience is required. You’ll gain hands-on exposure to industry-standard methods\, learn how to identify inefficiencies and improve processes\, and leave with a credential you can immediately add to your resume and talk about in interviews. Early registration is encouraged for discounted pricing.  \n\n\n\nDon’t miss this opportunity to earn a professional certification while still a student!! \n\n\n\n\nInformation/Registration
URL:https://engineering.wisc.edu/event/lean-green-belt-training/
LOCATION:WI
CATEGORIES:Biomedical Engineering,Chemical & Biological Engineering,Civil & Environmental Engineering,Departments,Electrical & Computer Engineering,Industrial & Systems Engineering,Materials Science & Engineering,Mechanical Engineering,Nuclear Engineering & Engineering Physics
ATTACH;FMTTYPE=image/png:https://engineering.wisc.edu/wp-content/uploads/2026/02/Lean-Green-Belt-Training.avif
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