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SUMMARY:BME Seminar Series: Wally Block\, PhD
DESCRIPTION:*Speaker Change\n\n\n\nGene Therapy for Rare Neurodegenerative Diseases: RARE will get us there\n\n\n\n\n\n\n\nWally Block\, PhDProfessorDepartment of Biomedical EngineeringUW-Madison \n\n\n\nRare monogenic neurological diseases affect about 0.5% of Americans at birth and are estimated to account for up to 40% of the workload in hospital pediatric practice. Current drug delivery methods struggle to overcome the Blood Brain Barrier (BBB)\, with 98% of small molecule drugs and 99% of monoclonal antibody therapies failing to cross the BBB. This barrier\, while protecting the brain\, creates significant challenges for drug delivery and patient treatment. \n\n\n\nConvection Enhanced Delivery (CED) is emerging as a promising solution\, circumventing the BBB with direct\, minimally invasive catheter-based infusion. Current CED surgical protocols distribute gene therapies are transforming the outlook for Huntington’s disease where only perhaps 1% of the brain needs to be altered genetically. In most rare neurodegenerative diseases however\, much larger volumes of the brain require will require treatment. \n\n\n\nNew government initiatives like ARPA-H THRIVE are making a 9-figure investment in genetic correction\, many of which will be focused on genetic correction for rare brain disorders. This talk will provide an overview of the biophysics technology being developed across a consortium centered at UW-Madison to get from 1% to 100% of brain coverage. The talk will present an argument why solving rare diseases will accelerate efforts to treat genetic approaches to much higher prevalence diseases such as Parkinson’s or Alzheimers. \n\n\n\nPrint PDF
URL:https://engineering.wisc.edu/event/bme-seminar-series-wally-block-phd/
LOCATION:1003 (Tong Auditorium) Engineering Centers Building\, 1550 Engineering Drive\, Madison\, WI\, 53706\, United States
CATEGORIES:Biomedical Engineering,Seminar
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ORGANIZER;CN="Department of Biomedical Engineering":MAILTO:bmehelp@bme.wisc.edu
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DTSTART;TZID=America/Chicago:20260219T130000
DTEND;TZID=America/Chicago:20260219T140000
DTSTAMP:20260404T215603
CREATED:20260213T182907Z
LAST-MODIFIED:20260213T182909Z
UID:10001459-1771506000-1771509600@engineering.wisc.edu
SUMMARY:MS&E Seminar Series: Ann Bolcavage
DESCRIPTION:UW-Madison Department of Materials Science and Engineering welcomes Ann Bolcavage. Her seminar\, “Environmental Barrier Coatings for Ceramic Matrix Composite Materials: Bridging the Gap from Laboratory to Engine”\, will take place on Thursday\, February 19\, from 1-2 p.m. in MS&E 265. \n\n\n\nBio \n\n\n\nDr. Ann Bolcavage is the Engineering Fellow for Coatings at Rolls-Royce plc.\, a global manufacturer of propulsion solutions for civil aerospace\, defense\, and power systems markets. She is responsible for the strategic development of critical coating materials and manufacturing technologies for surface engineering to provide through-life support for all products.  Over the course of her career\, Ann has focused on developing metallic and ceramic coatings and thin films\, and her expertise includes the measurement of process-structure-property relationships leading to optimized thermal spray\, chemical vapor deposition\, and physical vapor deposition processing methods for new and repaired aerospace and industrial gas turbine engine components. \n\n\n\nAnn joined Rolls-Royce Corporation in 2006 as a Senior Engineering Specialist in Indianapolis\, IN and subsequently held roles as Surface Engineering Manager (UK) and Chief of Materials Capability Acquisition before her appointment to the Rolls-Royce Engineering Fellowship in 2014.  She was also the Corporate Technical Liaison for key research programs in surface engineering at the Commonwealth Center for Advanced Manufacturing (Disputanta\, VA) and at the University of Virginia / Rolls-Royce UTC for Advanced Materials Systems.  Prior to joining Rolls-Royce\, Ann worked at Praxair Surface Technologies (now Linde AMT) in Indianapolis. \n\n\n\nIn recognition of her technical achievements and leadership\, Ann was appointed Fellow of ASM International in 2011.  She has been active in ASM for 40 years\, including leadership positions in the Indianapolis Chapter\, Board member of the Thermal Spray Society\, and ASM International Board of Trustees member.  Ann was also elected to the TSS Hall of Fame in 2025. \n\n\n\nAnn received her B.S. with honors in Materials Science and Engineering from Lehigh University and her M.S and Ph.D. in Metallurgical Engineering from the University of Wisconsin-Madison. She has remained active in writing technical publications\, giving conference and workshop presentations (9 invited)\, and has 23 patented inventions.  \n\n\n\nAbstract \n\n\n\nEnvironmental barrier coatings (EBCs) with rare-earth silicate-based compositions have increasingly become a preferred solution for the protective system to prevent accelerated degradation of silicon carbide-matrix / silicon carbide fiber ceramic matrix composite (CMC) components.  Within the harsh conditions of the gas turbine engine\, an EBC system must maintain thermophysical and thermomechanical stability and withstand degradation from the high gas velocities\, high temperatures\, high pressures\, and high-water vapor levels from combustion products.  Increasingly\, EBCs must also be resilient to the effects of ingested dust and siliceous debris (CMAS) from operation in arid\, volcanic\, or polluted regions.  The overall effects of these conditions on the coating materials system life and degradation rate are complex\, with multiple damage mechanisms in play over the course of the component lifecycle.  \n\n\n\nLaboratory / rig testing to assess EBC performance for any one property or damage mechanism is not wholly predictive and scalable to the likely performance of the coated component in the actual engine\, due to the complex interactions between them.  Often\, environmental testing cannot simulate the low concentration of species over many cycles\, specimen geometry is kept simple to facilitate rig design or simplify analysis\, and the relative severity of multiple degradation mechanisms can’t be accurately replicated.  As engine demonstration tests are extremely expensive\, it is desired to gain important data and insights about EBC systems earlier in the development lifecycle while staying grounded as close to operational reality as possible.  Examples and results are presented from laboratory and rig testing that demonstrate the materials and functional property gaps in understanding and what a recommended approach must incorporate to ensure robust learning is gained from concept to demonstration. 
URL:https://engineering.wisc.edu/event/mse-seminar-series-ann-bolcavage/
LOCATION:Wisconsin
CATEGORIES:Materials Science & Engineering,Seminar
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DTSTART;TZID=America/Chicago:20260219T143000
DTEND;TZID=America/Chicago:20260219T160000
DTSTAMP:20260404T215603
CREATED:20260211T165214Z
LAST-MODIFIED:20260211T165319Z
UID:10001457-1771511400-1771516800@engineering.wisc.edu
SUMMARY:ISyE - Website Portfolio Design Seminar
DESCRIPTION:Join our HFES student org for this Website Portfolio Design Seminar. This is a hands-on workshop which will cover the basics of building a website using GitHub.
URL:https://engineering.wisc.edu/event/isye-website-portfolio-design-seminar/2026-02-19/
LOCATION:1270 Mechanical Engineering\, 1513 University Ave\, Madison\, 53706
CATEGORIES:Departments,Industrial & Systems Engineering,Seminar,Student Org Event
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DTSTART;TZID=America/Chicago:20260219T160000
DTEND;TZID=America/Chicago:20260219T170000
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CREATED:20260115T173925Z
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UID:10001411-1771516800-1771520400@engineering.wisc.edu
SUMMARY:ME 150th Celebration: Distinguished Alumni\, Chris Schyvinck
DESCRIPTION:To celebrate 150 years of Mechanical Engineering at the University of Wisconsin – Madison\, the Department of Mechanical Engineering will feature distinguished alumni in mechanical engineering and engineering mechanics who have made a lasting impact on the field. Chris Schyvinck\, who received her bachelor’s (’89) in mechanical engineering\, is the CEO and President of SHURE. She has played a big role in the microphones and audio electronics industry\, which has led to exceptional results in product quality and corporate profitability. To learn more about Chris Schyvinck’s experience\, please join us for this installment of our ME 903: Graduate Student Lecture series. \n\n\n\nPresentation Abstract: This presentation reflects on Chris’ journey from mechanical engineer to CEO and the experiences\, lessons\, and mindset shifts that shaped her path along the way. Through three chapters—Engineering\, Managing\, and Leading—it highlights how curiosity\, continuous learning\, and strong partnerships helped guide her growth and leadership approach. \n\n\n\nBio: Christine Schyvinck is President\, CEO\, and Chairman of Shure Incorporated\, a global leader in audio technology. Since joining Shure in 1989 as a Quality Engineer\, she has held multiple leadership roles across engineering\, operations\, sales\, and global marketing. Under her direction\, Shure has expanded international operations\, boosted sales\, enhanced delivery performance\, and strengthened inclusive leadership and sustainability efforts. Appointed CEO in 2016\, Chris is only the fourth person to lead the Company. She holds a B.S. in Mechanical Engineering from UW–Madison and a Master’s in Engineering Management from Northwestern. She serves on various advisory and nonprofit boards\, including the Executives’ Club of Chicago and Blessings in a Backpack.
URL:https://engineering.wisc.edu/event/me-150th-celebration-distinguished-alumni-chris-schyvinck/
LOCATION:3M Auditorium\, rm 1106 Mechanical Engineering Building\, 1513 University Ave\, Madison\, 53711
CATEGORIES:Alumni events,Featured Guest Speaker,Mechanical Engineering,Seminar
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DTSTART;TZID=America/Chicago:20260220T120000
DTEND;TZID=America/Chicago:20260220T130000
DTSTAMP:20260404T215603
CREATED:20260120T211055Z
LAST-MODIFIED:20260219T173758Z
UID:10001419-1771588800-1771592400@engineering.wisc.edu
SUMMARY:Midwest Mechanics Seminar: Professor Bharath Ganapathisubramani
DESCRIPTION:The Mechanics Seminar Series is a weekly seminar given by campus and visiting speakers on topics across the spectrum of mechanics research (solids\, fluids\, and dynamics). This specific seminar is hosted in conjunction with the Midwest Mechanics Seminar Series. Professor Bharath Ganapathisubramani is a professor at University of South Hampton. \n\n\n\nPresentation Title: Vortex Dominated Flows: Can’t live with them…Can’t live without them… \n\n\n\nAbstract: Vortex-dominated flows are in abundance in engineering applications and natural environment. Vortical structures influence not only the flow field but also have major implications on forces and moments experienced by objects as well as noise generated by them. In this talk\, I will present results from work carried out in my group across different projects. We will focus on at least two case studies. The first is aimed at understanding the fluid-structure interactions in flow past porous bluff bodies while the second will focus on swimming efficiency of marine reptiles in Mesozoic era. These case studies will show that the behaviour of vortex interactions have a profound impact well beyond their specific application and that understanding these interactions can spawn new applications in varied areas including flow manipulation and bio-inspired vehicle design.  \n\n\n\nBio: Bharath Ganapathisubramani is a Professor of Experimental Fluid Mechanics in the Department of Aeronautics & Astronautics at the University of Southampton. He completed his Masters and PhD in Aerospace Engineering at the University of Minnesota and an undergraduate degree in Naval Architecture and Ocean Engineering at the Indian Institute of Technology-Madras. He was an Assistant Professor at Imperial College London and moved to Southampton as an Associate Professor. He currently serves as an Associate Editor for Experiments in Fluids and Flow. He is a Fellow of Royal Aeronautical Society and the American Physical Society as well as an Associate Fellow of AIAA.
URL:https://engineering.wisc.edu/event/midwest-mechanics-seminar-professor-bharath-ganapathisubramani/
LOCATION:1227 Engineering Hall\, 1415 Engineering Drive\, Madison\, WI\, 53706\, United States
CATEGORIES:Mechanical Engineering,Seminar
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