Biomedical Engineering

Electrical Manipulation of Biological Cells: Models and Applications Allen Garner, PhD, PEProfessor, Graduate Program ChairSchool of Nuclear EngineeringPurdue University Electric waveforms, including electric pulses (EPs) and alternating current (AC) fields, such as radiofrequency and high-power microwaves, can induce deleterious or beneficial effects that require additional characterization. We combine thermal models with the Smoluchowski equation to...

Molecular Imaging of the Tumor Microenvironment Marty Pagel, PhDProfessorDepartment of Medical PhysicsDepartment of RadiologyUniversity of Wisconsin-Madison Abstract:Tumor acidosis, hypoxia, and vascular perfusion are well-known characteristics of the tumor microenvironment. We have developed MRI, MR Fingerprinting, PET/MRI, electron paramagnetic resonance imaging (EPRI), and photoacoustic imaging (PAI) to quantitatively measure extracellular pH, oxygenation, and pharmacokinetic transport rates...

Molecular to Systemic Engineering of Immune Cells for Robust Immunotherapy Hua Wang, PhDAssociate ProfessorDepartment of Materials Science and EngineeringUniversity of Illinois at Urbana-Champaign Abstract:Immunotherapy has achieved significant clinical progress for the treatment of cancer and other diseases over the past decade, but challenges, including low patient responses, off-target side effects, and poor efficacy against solid...