Joshua Brockman Assistant Professor Department Biomedical Engineering Contact Engineering Centers Building 1550 Engineering Dr Madison, WI e: jmbrockman2@wisc.edu Featured news Focus on new faculty: Joshua Brockman reckons with the force of the immune system September 15, 2023 Education PhD 2020, Georgia Institute of TechnologyBS 2014, Ohio State University Awards 2019 Dept. of Biomedical Engineering, Georgia Institute of Technology, Excellence in Fundamental Research Award2018 National Cancer Institute/National Institute of Health, NCI Predoctoral to Postdoctoral Fellow (F99/K00)2015 National Science Foundation, NSF Graduate Research Fellowship Recent publications Jeffreys, N., Brockman, J., Zhai, Y., Ingber, D. E., & Mooney, D. J. (2024). Mechanical forces amplify TCR mechanotransduction in T cell activation and function. Applied Physics Reviews, 11(1).Zhang, D. K., Brockman, J., Adu-Berchie, K., Liu, Y., Binenbaum, Y., Lázaro, I., Sobral, M. C., Tresa, R., & Mooney, D. J. (2024). Subcutaneous biodegradable scaffolds for restimulating the antitumour activity of pre-administered CAR-T cells. Nature Biomedical Engineering, 1-11.Adu-Berchie, K., Brockman, J., Liu, Y., To, T. W., Zhang, D. K., Najibi, A. J., Binenbaum, Y., Stafford, A., Dimitrakakis, N., Sobral, M. C., & others, (2023). Adoptive T cell transfer and host antigen-presenting cell recruitment with cryogel scaffolds promotes long-term protection against solid tumors. Nature Communications, 14(1), 3546.Liu, Y., Adu-Berchie, K., Brockman, J., Pezone, M., Zhang, D. K., Zhou, J., Pyrdol, J. W., Wang, H., Wucherpfennig, K. W., & Mooney, D. J. (2023). Cytokine conjugation to enhance T cell therapy. Proceedings of the National Academy of Sciences, 120(1), e2213222120.Zhang, D. K., Adu-Berchie, K., Iyer, S., Liu, Y., Cieri, N., Brockman, J., Neuberg, D., Wu, C. J., & Mooney, D. J. (2023). Enhancing CAR-T cell functionality in a patient-specific manner. Nature Communications, 14(1), 506.Adu-Berchie, K., Liu, Y., Zhang, D. K., Freedman, B. R., Brockman, J., Vining, K. H., Nerger, B. A., Garmilla, A., & Mooney, D. J. (2023). Generation of functionally distinct T-cell populations by altering the viscoelasticity of their extracellular matrix. Nature biomedical engineering, 7(11), 1374-1391.Adu-Berchie, K., Brockman, J., Liu, Y., Zhang, D. K., Najibi, A. J., Stafford, A., Sobral, M. C., Binenbaum, Y., Dellacherie, M. O., & Mooney, D. J. (2022). Enhancing adoptive T cell therapy with synergistic host immune engagement promotes long-term protection against solid tumors. bioRxiv, 2022-09.Ma, V. P., Hu, Y., Kellner, A. V., Brockman, J., Velusamy, A., Blanchard, A. T., Evavold, B. D., Alon, R., & Salaita, K. (2022). The magnitude of LFA-1/ICAM-1 forces fine-tune TCR-triggered T cell activation. Science advances, 8(8), eabg4485.Blanchard, A., Combs, J. D., Brockman, J., Kellner, A. V., Glazier, R., Su, H., Bender, R. L., Bazrafshan, A. S., Chen, W., Quach, M. E., & others, (2021). Author Correction: Turn-key mapping of cell receptor force orientation and magnitude using a commercial structured illumination microscope. Nature Communications, 12(1), 5600.Blanchard, A. T., Combs, D., Rashid, S. A., Brockman, J., Duan, Y., Mattheyses, A. L., & Salaita, K. (2021). Diffraction-Limited Mapping of Integrin Force Vector Fields with Valid-Mfm. Biophysical Journal, 120(3), 357a. Courses BME 399 - Independent Study (Fall 2025)BME 790 - Master's Research and Thesis (Fall 2025)BME 799 - Advanced Independent Study (Fall 2025)BME 890 - Pre-dissertation Research (Fall 2025)BME 990 - Research and Thesis (Fall 2025)BME 399 - Independent Study (Summer 2025)BME 790 - Master's Research and Thesis (Summer 2025)BME 799 - Advanced Independent Study (Summer 2025)BME 890 - Pre-dissertation Research (Summer 2025)BME 990 - Research and Thesis (Summer 2025)BME 301 - Biomedical Engineering Design and Communication (Spring 2025)BME 399 - Independent Study (Spring 2025)BME 545 - Engineering Extracellular Matrices (Spring 2025)BME 890 - Pre-dissertation Research (Spring 2025)BME 990 - Research and Thesis (Spring 2025)BME 200 - Biomedical Engineering Design (Fall 2024)BME 300 - Biomedical Engineering Design and Leadership (Fall 2024)BME 399 - Independent Study (Fall 2024)BME 890 - Pre-dissertation Research (Fall 2024)BME 990 - Research and Thesis (Fall 2024)BME 890 - Pre-dissertation Research (Summer 2024)BME 545 - Engineering Extracellular Matrices (Spring 2024)BME 990 - Research and Thesis (Spring 2024)BME 200 - Biomedical Engineering Design (Fall 2023)BME 300 - Biomedical Engineering Design and Leadership (Fall 2023)BME 890 - Pre-dissertation Research (Fall 2023)