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Josh Brochman

Joshua Brockman

Assistant Professor
gscholar website
linkedin website

Department

Biomedical Engineering

Contact

Engineering Centers Building
1550 Engineering Dr
Madison, WI

Featured news

Focus on new faculty: Joshua Brockman reckons with the force of the immune system

September 15, 2023

  • PhD 2020, Georgia Institute of Technology
  • BS 2014, Ohio State University

  • 2019 Dept. of Biomedical Engineering, Georgia Institute of Technology, Excellence in Fundamental Research Award
  • 2018 National Cancer Institute/National Institute of Health, NCI Predoctoral to Postdoctoral Fellow (F99/K00)
  • 2015 National Science Foundation, NSF Graduate Research Fellowship

  • Jeffreys, N., Brockman, J., Zhai, Y., Ingber, D. E., & Mooney, D. J. (2024). Mechanical forces amplify TCR mechanotransduction in T cell activation and function. Applied Physics Reviews, 11(1).
  • Zhang, D. K., Brockman, J., Adu-Berchie, K., Liu, Y., Binenbaum, Y., Lázaro, I., Sobral, M. C., Tresa, R., & Mooney, D. J. (2024). Subcutaneous biodegradable scaffolds for restimulating the antitumour activity of pre-administered CAR-T cells. Nature Biomedical Engineering, 1--11.
  • Adu-Berchie, K., Brockman, J., Liu, Y., To, T. W., Zhang, D. K., Najibi, A. J., Binenbaum, Y., Stafford, A., Dimitrakakis, N., Sobral, M. C., & others, (2023). Adoptive T cell transfer and host antigen-presenting cell recruitment with cryogel scaffolds promotes long-term protection against solid tumors. Nature Communications, 14(1), 3546.
  • Liu, Y., Adu-Berchie, K., Brockman, J., Pezone, M., Zhang, D. K., Zhou, J., Pyrdol, J. W., Wang, H., Wucherpfennig, K. W., & Mooney, D. J. (2023). Cytokine conjugation to enhance T cell therapy. Proceedings of the National Academy of Sciences, 120(1), e2213222120.
  • Zhang, D. K., Adu-Berchie, K., Iyer, S., Liu, Y., Cieri, N., Brockman, J., Neuberg, D., Wu, C. J., & Mooney, D. J. (2023). Enhancing CAR-T cell functionality in a patient-specific manner. Nature Communications, 14(1), 506.
  • Adu-Berchie, K., Liu, Y., Zhang, D. K., Freedman, B. R., Brockman, J., Vining, K. H., Nerger, B. A., Garmilla, A., & Mooney, D. J. (2023). Generation of functionally distinct T-cell populations by altering the viscoelasticity of their extracellular matrix. Nature biomedical engineering, 7(11), 1374--1391.
  • Adu-Berchie, K., Brockman, J., Liu, Y., Zhang, D. K., Najibi, A. J., Stafford, A., Sobral, M. C., Binenbaum, Y., Dellacherie, M. O., & Mooney, D. J. (2022). Enhancing adoptive T cell therapy with synergistic host immune engagement promotes long-term protection against solid tumors. bioRxiv, 2022--09.
  • Ma, V. P., Hu, Y., Kellner, A. V., Brockman, J., Velusamy, A., Blanchard, A. T., Evavold, B. D., Alon, R., & Salaita, K. (2022). The magnitude of LFA-1/ICAM-1 forces fine-tune TCR-triggered T cell activation. Science advances, 8(8), eabg4485.
  • Blanchard, A., Combs, J. D., Brockman, J., Kellner, A. V., Glazier, R., Su, H., Bender, R. L., Bazrafshan, A. S., Chen, W., Quach, M. E., & others, (2021). Author Correction: Turn-key mapping of cell receptor force orientation and magnitude using a commercial structured illumination microscope. Nature Communications, 12(1), 5600.
  • Blanchard, A. T., Combs, D., Rashid, S. A., Brockman, J., Duan, Y., Mattheyses, A. L., & Salaita, K. (2021). Diffraction-Limited Mapping of Integrin Force Vector Fields with Valid-Mfm. Biophysical Journal, 120(3), 357a.

  • B M E 301 - Biomedical Engineering Design and Communication (Spring 2025)
  • B M E 399 - Independent Study (Spring 2025)
  • B M E 545 - Engineering Extracellular Matrices (Spring 2025)
  • B M E 890 - Pre-dissertation Research (Spring 2025)
  • B M E 990 - Research and Thesis (Spring 2025)
  • B M E 200 - Biomedical Engineering Design (Fall 2024)
  • B M E 300 - Biomedical Engineering Design and Leadership (Fall 2024)
  • B M E 399 - Independent Study (Fall 2024)
  • B M E 890 - Pre-dissertation Research (Fall 2024)
  • B M E 990 - Research and Thesis (Fall 2024)
  • B M E 890 - Pre-dissertation Research (Summer 2024)
  • B M E 545 - Engineering Extracellular Matrices (Spring 2024)
  • B M E 990 - Research and Thesis (Spring 2024)
  • B M E 200 - Biomedical Engineering Design (Fall 2023)
  • B M E 300 - Biomedical Engineering Design and Leadership (Fall 2023)
  • B M E 890 - Pre-dissertation Research (Fall 2023)