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Quentin Dudley

Quentin Dudley

Hunt-Hougen Assistant Professor

Quentin Dudley joined the Department of Chemical and Biological Engineering as an assistant professor in January 2024. He completed his PhD at Northwestern University, developing a new approach for prototyping enzyme pathways using cell-free protein synthesis. Afterward, he spent four years as a postdoctoral researcher at the Earlham Institute and John Innes Centre in Norwich, United Kingdom where he improved tools for engineering plants to produce valuable bioactive molecules such as strictosidine, a precursor to anticancer compounds. Before joining UW-Madison, he led the analytical chemistry team at the plant synthetic biology company Calyxt and was a field strategist for Speculative Technologies, a non-profit research organization.

The Dudley lab will be researching sustainable production of useful biomolecules with a particular focus on cell-free and plant synthetic biology.

Department

Chemical & Biological Engineering

Contact

3635, Engineering Hall
1415 Engineering Dr
Madison, WI

  • PhD 2017, Northwestern University
  • MS 2012, Univ. of Nebraska-Lincoln
  • BS 2011, Univ. of Nebraska-Lincoln

  • Plant synthetic biology
  • metabolic engineering
  • cell-free systems
  • genome editing

  • 2019 Gordon Research Seminar Plant Metabolic Engineering, Best Oral Presentation
  • 2016 Department of Chemical Engineering, Northwestern University, Travel Award
  • 2015 Northwestern University, Searle Teaching Certificate Program Practitioner
  • 2013 Molecular Biophysics Training Program Trainee
  • 2012 Northwestern University, Cabell Fellowship Recipient
  • 2011 University of Nebraska-Lincoln, Chancellor’s Scholar
  • 2011 Biological Systems Engineering Department, Univ. of Nebraska-Lincoln, Outstanding Senior
  • 2010 Univ. of Nebraska-Lincoln, President the Innocents Society (the Chancellor’s senior honorary)
  • 2007 National Merit Scholar

  • Tomaž, Š., Petek, M., Lukan, T., Pogačar, K., Stare, K., Teixeira Prates, E., Jacobson, D. A., Zrimec, J., Bajc, G., Butala, M., Pompe Novak, M., Dudley, Q., Patron, N., Taler-Verčič, A., Usenik, A., Turk, D., Prat, S., Coll, A., & Gruden, K. (2023). A mini-TGA protein modulates gene expression through heterogeneous association with transcription factors. Plant Physiology, 191(3), 1934-1952 https://doi.org/10.1093/plphys/kiac579
  • Tomaž, Š., Petek, M., Lukan, T., Pogačar, K., Stare, K., Teixeira Prates, E., Jacobson, D. A., Zrimec, J., Bajc, G., Butala, M., & Dudley, Q. (2023). A mini-TGA protein modulates gene expression through heterogeneous association with transcription factors. Plant physiology, 191(3), 1934-1952.
  • Vollheyde, K., Dudley, Q., Yang, T., Oz, M. T., Mancinotti, D., Fedi, M. O., Heavens, D., Linsmith, G., Chhetry, M., Smedley, M. A., & others, (2023). An improved Nicotiana benthamiana bioproduction chassis provides novel insights into nicotine biosynthesis. New Phytologist, 240(1), 302--317.
  • Dudley, Q., Raitskin, O., & Patron, N. J. (2022). Cas9-mediated targeted mutagenesis in plants. In Plant Synthetic Biology: Methods and Protocols (p. 1-26). Springer US New York, NY.
  • Dudley, Q., Jo, S., Guerrero, D. A., Chhetry, M., Smedley, M. A., Harwood, W. A., Sherden, N. H., O’Connor, S. E., Caputi, L., & Patron, N. J. (2022). Reconstitution of monoterpene indole alkaloid biosynthesis in genome engineered Nicotiana benthamiana. Communications biology, 5(1), 949.
  • Dudley, Q., Cai, Y., Kallam, K., Debreyne, H., Carrasco Lopez, J. A., & Patron, N. J. (2021). Biofoundry-assisted expression and characterization of plant proteins. Synthetic Biology, 6(1), ysab029.
  • Cai, Y., Dudley, Q., & Patron, N. J. (2021). Measurement of transgene copy number in plants using droplet digital PCR. Bio-protocol, 11(13), e4075-e4075.
  • Dudley, Q. (2020). Cell-Free Protein Synthesis As a Tool for Prototyping Metabolic Pathways and Guiding Plant Genome Engineering. In 2020 Virtual AIChE Annual Meeting.
  • Karim, A. S., Dudley, Q., Juminaga, A., Yuan, Y., Crowe, S. A., Heggestad, J. T., Garg, S., Abdalla, T., Grubbe, W. S., Rasor, B. J., & others, (2020). In vitro prototyping and rapid optimization of biosynthetic enzymes for cell design. Nature Chemical Biology, 16(8), 912-919.
  • Dudley, Q., Karim, A. S., Nash, C. J., & Jewett, M. C. (2020). In vitro prototyping of limonene biosynthesis using cell-free protein synthesis. Metabolic Engineering, 61, 251-260.

  • CBE 326 - Momentum and Heat Transfer Operations (Spring 2026)
  • CBE 599 - Special Problems (Spring 2026)
  • CBE 890 - Pre-Dissertator's Research (Spring 2026)
  • CBE 990 - Thesis-Research (Spring 2026)
  • BME 560 - Biochemical Engineering (Fall 2025)
  • CBE 560 - Biochemical Engineering (Fall 2025)
  • CBE 599 - Special Problems (Fall 2025)
  • CBE 890 - Pre-Dissertator's Research (Fall 2025)
  • CBE 990 - Thesis-Research (Fall 2025)
  • CBE 599 - Special Problems (Summer 2025)
  • CBE 890 - Pre-Dissertator's Research (Summer 2025)
  • CBE 326 - Momentum and Heat Transfer Operations (Spring 2025)
  • CBE 599 - Special Problems (Spring 2025)
  • CBE 890 - Pre-Dissertator's Research (Spring 2025)
  • BME 560 - Biochemical Engineering (Fall 2024)
  • CBE 560 - Biochemical Engineering (Fall 2024)
  • CBE 599 - Special Problems (Fall 2024)
  • CBE 890 - Pre-Dissertator's Research (Fall 2024)
  • CBE 599 - Special Problems (Summer 2024)
  • CBE 890 - Pre-Dissertator's Research (Summer 2024)
  • BME 560 - Biochemical Engineering (Spring 2024)
  • CBE 560 - Biochemical Engineering (Spring 2024)
  • CBE 599 - Special Problems (Spring 2024)
  • CBE 890 - Pre-Dissertator's Research (Spring 2024)