Department of Biomedical Engineering

Mapping cellular responses to perturbations with dynamic computational imaging and AI Shalin Mehta, PhDPlatform LeaderComputational MicroscopyChan Zuckerberg Biohub co-sponsors: Morgridge Institute for Research and the Center for Quantitative Cellular Imaging...

The Death and Re-Birth of the Intervertebral Disc Cell Lori A. Setton, PhDLopata Distinguished Professor and Chair of Biomedical EngineeringMcKelvey School of Engineering, Washington University in St. Louis Corrine Bahr Memorial Lecture Abstract:Intervertebral disc disorders are among the greatest contributors to pain and disability annually, such that low back pain and neck pain are ranked...

Nanotransfection-driven gene and cell therapies Daniel Gallego-Perez, PhDEdgar C. Hendrickson Chair in Biomedical EngineeringProfessor, Surgery GeneralThe Ohio State University Abstract:Gene and engineered cell therapies hold transformative potential for treating a wide range of conditions. However, current approaches face significant practical and translational challenges, including a heavy reliance on viral vectors and high variability, which often...

Analyzing Brain-Wide Function Using New Molecular Imaging Tools Alan Jasanoff, PhDProfessor of Biological Engineering and Brain and Cognitive SciencesMassachusetts Institute of Technology Abstract:Behavior and cognition depend on the integrated action...

Biomechanics of Thoracic Aortic Aneurysms Jessica Wagenseil, DScProfessor, Mechanical Engineering and Materials ScienceVice Dean for Faculty AdvancementMcKelvey School of EngineeringWashington University Abstract:Thoracic aortic aneurysms are a dilation of the aortic wall that can be asymptomatic for many years until they dissect or rupture. Dissection or rupture is associated with a high mortality rate. Surgical replacement...

Electrical Manipulation of Biological Cells: Models and Applications Allen Garner, PhD, PEProfessor, Graduate Program ChairSchool of Nuclear EngineeringPurdue University Electric waveforms, including electric pulses (EPs) and alternating current (AC) fields,...

Molecular Imaging of the Tumor Microenvironment Marty Pagel, PhDProfessorDepartment of Medical PhysicsDepartment of RadiologyUniversity of Wisconsin-Madison Abstract:Tumor acidosis, hypoxia, and vascular perfusion are well-known characteristics of the tumor microenvironment. We have developed MRI, MR Fingerprinting, PET/MRI, electron paramagnetic resonance imaging (EPRI), and photoacoustic imaging (PAI) to quantitatively measure extracellular pH, oxygenation, and pharmacokinetic transport rates...