Materials define the major technological ages of humankind and are central to overcoming challenges in areas that include energy, the environment and human health. We are developing materials’ most impactful new capabilities, including atomic and nanoscale control, 3D printing, low-dimensional and quantum properties, and predictive simulation and machine learning. Our facilities include outstanding equipment for synthesis, processing and characterization, and some of the most advanced tools in the world, from nano-calorimetry to ultrafast electron microscopy.